ABSTRACT
Introduction: To study the clinical presentation and renal outcomes in SARS-COV infected patients with renal dysfunction. Method(s): In this single center observational study, SARS-COV infected inpatients referred to Nephrology Dept. over a period of 4 months were classified in to 2 groups. 1) De novo AKI and 2) Chronic kidney disease- includes CKD stage 1-4, CKD stage 5D (Maintenance Hemodialysis- MHD) and CKD 5T (Post kidney transplant- KTx). Result(s): In this observational study total 184 patients were included. Mean age was 66.1 + 8.2 years, 68 % males. 51% patients were diabetic, 79% hypertensive, 37.5% underlying heart disease (IHD + LVD) and 18.5% were having chronic lung disease. 52% MHD group patient had no respiratory complaints. Loose motion was most common in KTx group (32%) and altered sensorium was most common in MHD group (22%). Table-1: Presentation [Formula presented] Table-2A: Outcomes [Formula presented] Table 2B: Outcomes [Formula presented] Mechanical Ventilator required in 9% KTx, 35 % MHD, 42 % CKD and 55 % De novo AKI. Conclusion(s): In this cohort of renal patients in the first 4 months of the COVID pandemic, it was observed that: 1. Typical respiratory complaints were less common among patients on MHD (p <0.05). 2. De novo AKI patients had higher mortality as compared to CKD patients (p <0.005). 3. Patients who required de novo initiation of RRT had a worse outcome. Mortality in patients who were initiated on RRT was 93 % as compared to 19.5 % in MHD patients (p <0.0001). 4. Post kidney transplant patients had a better outcome in terms of mortality and complete GFR recovery as compared to other CKD Groups (p < 0.05). No conflict of interestCopyright © 2021